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COMPLEMENT C5 CONVERTASE, ALTERNATIVE PATHWAY
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DeCS
Descriptor
English
:
Complement C5 Convertase, Alternative Pathway
Descriptor
Spanish
:
C5 Convertasa de la Vía Alternativa del Complemento
Descriptor
Portuguese
:
C5 Convertase da Via Alternativa do Complemento
Tree Number:
D12.776.124.486.274.045.387.500.750
Definition
English
:
A
serine
protease that cleaves multiple
COMPLEMENT C5
into
COMPLEMENT C5A
(anaphylatoxin) and
COMPLEMENT C5B
in the ALTERNATIVE
COMPLEMENT ACTIVATION
PATHWAY. It is the complex of ALTERNATIVE PATHWAY
C3 CONVERTASE
(C3bBb) with an additional
COMPLEMENT C3B
, or C3bBb3b.
Pharmacological Action:
Immunologic Factors
History Note
English
:
2006
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
50831
Unique Identifier:
D051566
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS